Description
Product Characteristics:
Aliases: 5033428N14Rik antibody, amn antibody, Amnion associated transmembrane protein antibody, Amnionless antibody, Amnionless homolog antibody, AMNLS_HUMAN antibody, AV002116 antibody, PRO1028 antibody, Protein amnionless antibody, Type I transmembrane protein antibody, UNQ513/PRO1028 antibody, Visceral endoderm specific type 1 transmembrane protein antibody
Target Information: The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]